Jeffrey Tasker, Ph.D.
Director, Neuroscience Program
Catherine and Hunter Pierson Chair in Neuroscience
Professor of Cell and Molecular Biology
Email: tasker@tulane.edu
Web site: http://www.tulane.edu/~tasker/homepage/taskerhome.htm
University of Bordeaux, France, Neuroscience, 1986.
Professor of Cell and Molecular Biology. Neurophysiology of neuroendocrine systems of the mammalian hypothalamus involved in stress, fluid and energy homeostasis and reproductive function using patch-clamp electrophysiology in brain slices, molecular biology and immunohistochemistry.
Komendantov, A., Trayanova, N. and Tasker, J.G. (2007) Somato-dendritic mechanisms underlying the electrophysiological properties of hypothalamic magnocellular neuroendocrine cells: A multicompartmental model study. Journal of Computational Neuroscience May 5; [Epub ahead of print]
Malcher-Lopes, R., Di, S., Marcheselli, V.L., Weng, F.-J., Stuart, C.T., Bazan, N.G. and Tasker, J.G. (2006) Opposing crosstalk between leptin and glucocorticoids rapidly modulates synaptic excitation via endocannabinoid release. Journal of Neuroscience 26:6643-6650.
Tasker J.G., Di, S. and Malcher-Lopes, R. (2006) Rapid Glucocorticoid Signalling via Membrane-Associated Receptors. Endocrinology 147:5549-5556. (review)
Tasker, J.G. (2006) Rapid Glucocorticoid Actions in the Hypothalamus as a Mechanism of Homeostatic Integration. Obesity 14(suppl 5):259S-265S. (review)
Boudaba, C. and Tasker, J.G. (2006) Internuclear coupling of hypothalamic magnocellular nuclei by glutamate synaptic circuits. American Journal of Physiology - Regulatory, Integrative and Comparative Physiology 291:R102-111
Di, S., Boudaba, C., Popescu, I.R., Weng, F.-J., Harris, C., Marcheselli, V.L., Bazan, N.G. and Tasker, J.G. (2005) Activity-dependent release and actions of endocannabinoids in the rat hypothalamic supraoptic nucleus. Journal of Physiology 569:751-760.
Di, S, Malcher-Lopes, R., Marcheselli, V.L., Bazan, N.G. and Tasker, J.G. (2005) Rapid glucocorticoid-mediated endo-cannabinoid release and opposing regulation of glutamate and GABA inputs to hypothalamic magnocellular neurons. Endocrinology 146:4292-4301.
Di, S. and Tasker, J.G. (2004) Dehydration-induced synaptic plasticity in magnocellular neurons of the hypothalamic supraoptic nucleus. Endocrinology 145:5141-5149.
Boudaba, C., Linn, D.M. and Tasker, J.G. (2003) Increased tonic activation of presynaptic metabotropic glutamate receptors in the supraoptic nucleus following chronic dehydration. Journal of Physiology 551:815-823.
Di, S., Malcher-Lopes, R., Halmos, K.Cs. and Tasker, J.G. (2003) Non-genomic glucocorticoid inhibition via endocannabinoid release in the hypothalamus: a fast feedback mechanism. Journal of Neuroscience 23:4850-4857.
Boudaba, C., Di, S. and Tasker, J.G. (2003) Presynaptic noradrenergic regulation of glutamate inputs to rat hypothalamic magnocellular neurons. Journal of Neuroendocrinology 15:803-810.
Luther, J.L., Daftary, S.S., Boudaba, C., Gould, G.C., Halmos, K.Cs. and Tasker, J.G. (2002) Neurosecretory and non-neurosecretory parvocellular neurons of the hypothalamic paraventricular nucleus express distinct electrophysiological properties. Journal of Neuroendocrinology 14:929-932.
Herman, J.P, Tasker, J.G., Ziegler, D.R. and Cullinan, W.E. (2002) Paraventricular hypothalamic stress integration: Limbic connections with local circuit neurons. Pharmacology, Biochemistry and Behavior 71:457-468.
Herman, J.P., Cullinan, W.E., Ziegler, D.R. and Tasker, J.G. (2002) Role of the paraventricular nucleus microenvironment in stress integration. European Journal of Neuroscience 16:381-385.